1,2-Propanedione, 1-(4-chlorophenyl)-

1,2-Propanedione, 1-(4-chlorophenyl)- - Names and Identifiers

Name	1-(4-Chlorophenyl)-1,2-propandione
Synonyms	4-Chloro-2'-oxopropiophenone 1-(4-CHLOROPHENYL)-1,2-PROPANDIONE Chlorophenylpropandione 1412()---- 1-(4-Chlorophenyl)-1,2-propandione 1-(4-CHLOROPHENYL)-1,2-PROPANEDIONE 1-(4-CHLOROPHENYL)PROPANE-1,2-DIONE 1,2-Propanedione, 1-(4-chlorophenyl)- 4'-Chloro-2-oxopropiophenone, 1-(4-Chlorophenyl)-1,2-dioxopropane
CAS	10557-21-8
InChI	InChI=1/C9H7ClO2/c1-6(11)9(12)7-2-4-8(10)5-3-7/h2-5H,1H3

1,2-Propanedione, 1-(4-chlorophenyl)- - Physico-chemical Properties

Molecular Formula	C9H7ClO2
Molar Mass	182.6
Density	1.2700 g/cm3
Melting Point	30-32
Boling Point	60-65/0.02bar
Flash Point	115°C
Vapor Presure	0.00474mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.538

1,2-Propanedione, 1-(4-chlorophenyl)- - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

1,2-Propanedione, 1-(4-chlorophenyl)- - Introduction

1-(4-Chlorophenyl)-1,2-propanedione (also known as 4-chloroacetophenone) is an organic compound. It has a molecular formula of C9H7ClO2 and a molecular weight of 182.60g/mol. The following is a description of its nature, use, preparation and safety information:

Nature:
1-(4-Chlorophenyl)-1,2-propanedione is a colorless to slightly yellow solid with a special aromatic odor. It has a melting point of about 67-71 degrees Celsius and a boiling point of about 317 degrees Celsius. It is well soluble in solvents such as ethyl acetate, ether and dichloromethane. This compound is a common reagent in organic synthesis.

Use:
1-(4-Chlorophenyl)-1,2-propanedione is commonly used as an intermediate in organic synthesis. It can be used to synthesize chemicals such as various drugs, dyes and fungicides. In addition, it can also be used as an additive for coatings and resins, as well as a catalyst for organic synthesis reactions.

Preparation Method:
1-(4-Chlorophenyl)-1,2-propanedione can be obtained by reacting ethyl acetate with 4-chlorobenzaldehyde under alkaline conditions. The reaction is generally carried out under reflux conditions and requires an appropriate amount of base catalyst.

Safety Information:
1-(4-Chlorophenyl)-1,2-propanedione has no reported hazards under normal use conditions. However, it is important to follow appropriate safety practices, such as wearing appropriate personal protective equipment and avoiding contact with skin and eyes. In addition, it should be stored in a sealed container, away from fire and oxidizing agents. If necessary, it should be used in a well-ventilated place. If inhaled or exposed to the compound, seek medical help immediately.

Last Update：2024-04-09 20:52:54